Northbound Interstate 5 was closed on the Grapevine Friday night after a semi truck which may have lost its brakes crashed while coming down the hill.
The truck hit at least two other vehicles, jackknifed, rolled onto its side and burst into flames, CHP logs indicated.
The accident happened just before 10 pm and led to a complete closure of northbound lanes. By 10:30 two northbound lanes were back open, with lanes 3 and 4 said to be closed indefinitely.
No injuries were immediately reported.